New standard of neuroimaging markers of cerebral small vessel disease

XU Qun

doi:10.12022/jnnr.2016-0009

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Journal of Neurology and Neurorehabilitation ›› 2016, Vol. 12 ›› Issue (1) : 17-23. DOI: 10.12022/jnnr.2016-0009

Comment on Guideline

New standard of neuroimaging markers of cerebral small vessel disease

XU Qun

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Abstract

Cerebral small vessel disease (CSVD) is a common disease accompanied by aging and is also usually concomitant with neurodegeneration diseases, exacerbating cognitive impairment and physical disability. The lack of consistency of terminology, definition, image acquisition and scientific report of CSVD hampers the further understanding of effects of CSVD on pathophysiological and clinical features of common neurodegenerative diseases. A working group of global research specialists made a comprehensive review of neuroimaging markers of CSVD. The standard of interpretation of terminology and definition of six neuroimaging markers indicating key characteristic manifestations of CSVD, minimum standard for image acquisition and analysis, agreement on scientific reporting of neuroimaging features of CSVD, and new imaging methods for early detection of CSVD, were developed in 2012. These six neuroimaging markers include recent small subcortical infarcts, lacune of presumed vascular origin, white matter hyperintensities of presumed vascular origin, perivascular space, cerebral microbleeds and brain atrophy. The new standard should not be applied only to research work but also to the clinical practice, in order to improve the standardization of interpretation, acquisition and reporting of neuroimaging features of CSVD.

Key words

Cerebral small vessel disease / Neuroimaging / Magnetic resonance imaging / Standard

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XU Qun. New standard of neuroimaging markers of cerebral small vessel disease[J]. Journal of Neurology and Neurorehabilitation. 2016, 12(1): 17-23 https://doi.org/10.12022/jnnr.2016-0009

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