Neuroinflammation in ischemic stroke

ZHI Nan; XU Qun

doi:10.12022/jnnr.2016-0010

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Journal of Neurology and Neurorehabilitation ›› 2016, Vol. 12 ›› Issue (1) : 41-46. DOI: 10.12022/jnnr.2016-0010

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Neuroinflammation in ischemic stroke

ZHI Nan, XU Qun

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Abstract

Neuroinflammation plays an important role in pathological injury after ischemic stroke. Increasing evidence suggests that neuroinflammation is a double-edged sword, as it not only exacerbates secondary brain injury in the acute stage of stroke, but also beneficially contributes to brain recovery after stroke. This paper reviews the key factors involved in neuroinflammation after ischemic stroke, including inflammatory cells, inflammatory mediators and adhesion molecules, describing their possible detrimental and protective effects in stroke. This review also briefly introduces recently studies about the advances and future perspectives in neuroinflammation after ischemic stroke.

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Stroke / Neuroinflammation / Inflammatory cells / Inflammatory mediators

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ZHI Nan, XU Qun. Neuroinflammation in ischemic stroke[J]. Journal of Neurology and Neurorehabilitation. 2016, 12(1): 41-46 https://doi.org/10.12022/jnnr.2016-0010

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