Molecular and genetic mechanism of vascular dementia

LIU Xiaohui; LIU Xueyuan

doi:10.12022/jnnr.2016-0041

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Journal of Neurology and Neurorehabilitation ›› 2016, Vol. 12 ›› Issue (2) : 87-93. DOI: 10.12022/jnnr.2016-0041

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Molecular and genetic mechanism of vascular dementia

LIU Xiaohui, LIU Xueyuan

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Abstract

With the increasing incidence of dementia, more and more attention has been given to this disease. It has already been a clinical difficult problem threatening the health of mankind, especially for the aged people. After Alzheimer's disease, vascular dementia (VaD) is the second leading cause of senile dementia, including ischemic or hemorrhagic cerebrovascular diseases or a variety of clinical dementia due to low blood flow induced by heart and circulatory disorders. VaD is a promising disease for prevention and treatment, and it has been a hot topic in recent years. Therefore, this article summarizes the recent advances in molecular and genetic mechanism of VaD.

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Dementia, vascular / Genetic / Genes / Molecular mechanism

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LIU Xiaohui, LIU Xueyuan. Molecular and genetic mechanism of vascular dementia[J]. Journal of Neurology and Neurorehabilitation. 2016, 12(2): 87-93 https://doi.org/10.12022/jnnr.2016-0041

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Funding

General Project of National Natural Science Foundation of China (No. 81371212); Key Funding Project of Shanghai Science and Technology Committee (No. 13411951102, 13JC1404002)