The role of cerebrovascular reserve in ischemic stroke and its research progress

YANG Xue; WANG Yan

doi:10.12022/jnnr.2017-0054

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Journal of Neurology and Neurorehabilitation ›› 2017, Vol. 13 ›› Issue (4) : 213-220. DOI: 10.12022/jnnr.2017-0054

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The role of cerebrovascular reserve in ischemic stroke and its research progress

YANG Xue, WANG Yan

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Abstract

Cerebral blood vessel has the ability to automatically adjust the blood flow to the brain and against the damage of acute or chronic cerebral perfusion pressure alteration to meet the needs of brain metabolism during the occurrence of ischemic stroke. Through this physiological mechanism which is named as cerebrovascular reserve (CVR), the brain can get through the crisis. As a milestone of the research in the pathophysiology of ischemic stroke, however, CVR has not been widely recognized, which restricts the clinical application of CVR in further use as a routine reference index for the treatment of ischemic stroke. In this paper, the definition of CVR and its physiological mechanism, evaluation and intervention, and the progress in clinical application are systematically reviewed.

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Ischemic stroke / Cerebrovascular reserve / Clinical application

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YANG Xue, WANG Yan. The role of cerebrovascular reserve in ischemic stroke and its research progress[J]. Journal of Neurology and Neurorehabilitation. 2017, 13(4): 213-220 https://doi.org/10.12022/jnnr.2017-0054

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