Parkinson’s disease is a common degenerative disease of the central nervous system. It is characterized by muscle rigidity, static tremor, bradykinesia and other non-motor symptoms such as hyposmia, constipation and depression, and it brings inconvenience to patients’ lives. Exercise therapy plays an irreplaceable role in enhancing the living ability and quality of life of patients with Parkinson’s disease. Constraint-induced movement therapy as one of the progressively movement therapies can alter the disuse-induced enhancement process of the injured limbs and improve the physical function with repeated and intensive training. This paper discusses the origin and possible mechanism in constraint-induced movement therapy, then expounds the application of constraint-induced movement therapy in Parkinson’s disease.