Exploring preventive methods for vascular cognitive impairment based on the integration of traditional Chinese medical classics and modern medicine

Chunmei SHI, Henghao MA, Ruifang XU, Weidong PAN

Journal of Neurology and Neurorehabilitation ›› 2026, Vol. 22 ›› Issue (2) : 141-147.

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Journal of Neurology and Neurorehabilitation ›› 2026, Vol. 22 ›› Issue (2) : 141-147. DOI: 10.12022/jnnr.2025-0220
Vascular Dementia·Integrated Medicine of Neurology

Exploring preventive methods for vascular cognitive impairment based on the integration of traditional Chinese medical classics and modern medicine

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Abstract

Vascular cognitive impairment (VCI) refers to a clinical syndrome primarily characterized by cognitive dysfunction caused by damage to brain tissue due to cerebrovascular disease. Its etiology is complex and diverse, encompassing underlying diseases, genetics, immunology, environmental factors, and other aspects. Most cases of VCI exhibit a chronic, insidious, and progressive onset, involving multiple clinical stages. Currently, modern medicine primarily focuses on treating individual etiologies, with considerable research on stroke prevention and treatment. Clinically, it is advisable to follow modern medical methods, control controllable risk factors, and intervene and treat early to achieve better primary or secondary prevention effects and delay disease progression. Regarding the cognitive impairment associated with VCI, modern medicine has not yet discovered effective therapeutic drugs. However, ancient Chinese medical texts contain treatment plans for corresponding conditions. Therefore, combining basic western medical treatment with traditional Chinese medicine (TCM) for the prevention and treatment of this disease has become a current research hotspot. This paper aims to explore the advancements in the prevention of VCI by collating preventive measures for VCI in ancient Chinese medical literature and combining them with modern medical methods, providing a reference for clinical practice.

Key words

Vascular cognitive impairment / Ancient Chinese medicine / Integrative Medicine / New progress / Review

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Chunmei SHI, Henghao MA, Ruifang XU, Weidong PAN. Exploring preventive methods for vascular cognitive impairment based on the integration of traditional Chinese medical classics and modern medicine[J]. Journal of Neurology and Neurorehabilitation. 2026, 22(2): 141-147 https://doi.org/10.12022/jnnr.2025-0220

References

[1] 中国卒中学会血管性认知障碍分会. 中国血管性认知障碍诊疗指南[J]. 中华医学杂志, 2024, 104(31):2881-2894.
[2] 戴玲慧, 李伟峰. 线粒体稳态在血管性认知障碍中的研究进展[J]. 实用医学杂志, 2025, 41(12):1936-1944.
[3] TATJANA R, MAGDALENA T, TAYLOR A, et al. Vascular cognitive impairment (VCI)[J]. Neurotherapeutics, 2022, 19(1):68-88.
[4] 张兴棠, 方兴, 王瑞, 等. 活血化痰颗粒治疗痰瘀阻窍证脑梗死后血管性认知功能障碍的临床观察[J]. 中西医结合心脑血管病杂志, 2023, 21(3):529-531.
[5] 潘卫东. 基于个体化治疗的神经病学精准医疗与辨证论治[J]. 神经病学与神经康复学杂志, 2016, 12(2):57-63.
[6] 姚洁, 朱倩, 褚丽芳, 等. 脑卒中后并发血管性认知功能障碍与血清PTEN、HDAC3水平的关系及危险因素[J]. 疑难病杂志, 2022, 21(10):1030-1034, 1046.
[7] 王龙海, 黄志强. 脑小血管病所致血管性认知功能障碍患者VEGF hs-CRP水平及脑血流灌注的临床意义[J]. 中国实用神经疾病杂志, 2022, 25(10):1226-1231.
[8] 曹宇凤, 仲建刚, 郭宏敏. 郭宏敏教授运用养阴和瘀通窍汤治疗脑小血管病性非痴呆型血管性认知功能障碍经验撷萃[J]. 中医药信息, 2018, 35(6):89-92.
[9] 黄庆嘉, 陈炜, 吴林, 等. 中医药治疗血管性痴呆的研究进展[J]. 湖南中医杂志, 2018, 34(12):138-140.
[10] 黄文彬, 郑贤辉, 黄苏萍, 等. 探析脾胃与情志病[J]. 福建中医药, 2017, 48(3):49-50.
[11] 张家欢, 方兴, 徐秋凤, 等. 基于"瘀毒"与"自噬"理论的关系探讨脑小血管性认知功能障碍的病机及通窍活血汤的治疗机制[J]. 中西医结合心脑血管病杂志, 2023, 21(21):3956-3962.
[12] 李果, 高云水, 马守文, 等. 基于"络病理论"探讨血管性痴呆的诊治[J]. 中医药临床杂志, 2022, 34(11):2004-2007.
[13] 姜文斐, 汤雅馨, 潘卫东. 认知储备能与认知功能障碍的新进展[J]. 中国临床神经科学, 2016, 24(2):239-243.
[14] 陈婷, 梁红梅, 吴伟, 等. 国医大师邓铁涛教授益气除痰活血法治疗血管性痴呆经验[J]. 中华中医药杂志, 2016, 31(7):2598-2600.
[15] 王柏慧, 张立德, 程岩岩, 等. 从脾论治高血压病与血管性痴呆的相关性[J]. 实用中医内科杂志, 2021, 35(2):46-48.
[16] 杨杰, 王平, 王广, 等. 基于"线粒体-氧化应激"损伤机制从"痰"论治血管性痴呆[J].中国中医内科基础医学杂志, 2024, 30(2):199-203.
[17] 唐农, 胡跃强, 吴林, 等. 益肺宣肺降浊胶囊治疗血管性痴呆的临床疗效[J]. 中国老年学杂志, 2016, 36(4):843-844.
[18] 劳祎林, 陈炜, 伍媛, 等. 探讨脑肠轴与从肺论治观治疗血管性痴呆研究进展[J]. 辽宁中医药大学学报, 2021, 23(4):130-135.
[19] 杨新宁, 李彦杰, 秦合伟, 等. SIRTl在血管性认知障碍中的作用[J]. 协和医学杂志, 2024, 15(5):1124-1130.
[20] YOU T Y, WANG Y Z, CHEN S F, et al. Vascular cognitive impairment: Advances in clinical research and management[J]. Chin Med J (Engl), 2024, 137(23):2793-2807.
[21] 王萍, 梁燕, 高霞. 血管性知障碍药物治疗的研究进展[J]. 疑难病杂志, 2025, 24(6):757-760.
[22] 李泽琼, 徐峰, 兰小路, 等. 基于肝肺气机失调论治血管性痴呆[J]. 世界中西医结合杂志, 2022, 17(6):1261-1264.
[23] 赵捷, 赵明, 裴卉, 等. 基于?灵枢·本神?探讨从"心-脾-肾"轴理论论治血管性痴呆[J]. 上海中医药杂志, 2024, 58(5):41-46.
[24] 刘建军, 汪庭龙, 江丽萍, 等. 温肺降浊法治疗血管性痴呆探讨[J]. 浙江中医杂志, 2018, 53(11):815-816.
[25] 李柏, 金妍, 王栋先, 等. 基于基于血浊理论辨治脑病研究进展[J]. 山东中医杂志, 2025, 44(1):112-117.
[26] 陈炜, 胡跃强, 吴林, 等. 三焦次第疗法治疗血管性痴呆对神经功能缺损及行为能力的影响[J]. 中华中医药学刊, 2020, 38(11):70-73.
[27] 廖健颖, 朱蔚文, 李又福, 等. 皮质下缺血性脑血管病患者不同脑区脑白质病变与血管性认知功能损伤的相关性研究[J]. 实用心脑肺血管病杂志, 2020, 28(11):48-53.
[28] SANTISTEBAN M M, COSTANTINO I, DANIELA C. Hypertension, neurovascular dysfunction, and cognitive impairment[J]. Hypertension, 2022, 80(1):22-34.
[29] MUNRO C A. The concept of mild cognitive impairment: A victim of its ubiquity[J]. Int Psychogeriatr, 2018, 30(10):1423-1425.
[30] 张贵强. 血管性认知障碍诊治进展[J]. 黑龙江医学, 2024, 48(5):630-633, 637.
[31] 刘玲, 马英血管性认知功能障碍可干预危险因素研究进展[J]. 四川医学, 2019, 40(6):633-640.
[32] BASKARAN C, CUNNINGHAM B, PLESSOW F, et al. Estrogen replacement improves verbal memory and executive control in oligomenorrheic/amenorrheic athletes in a randomized controlled trial[J/OL]. J Clin Psychiatry, 2017, 78(5):e490-e497[2025-07-26]. .
[33] 郭丰, 闵连秋. 血管性认知功能障碍与常规检查的相关性分析[J]. 中国现代医学杂志, 2019, 29(4):88-93.

Funding

National Project for the Inheritance and Development of Traditional Chinese Medicine in Shanghai Pudong New Area (Famous TCM doctor in Shanghai Pudong)(PDZY-2025-0724)
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