The "cortical ribbon sign"

Yuanmei PAN, Ying CHEN, Gang WANG

Journal of Neurology and Neurorehabilitation ›› 2026, Vol. 22 ›› Issue (2) : 168-172.

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Journal of Neurology and Neurorehabilitation ›› 2026, Vol. 22 ›› Issue (2) : 168-172. DOI: 10.12022/jnnr.2025-0332
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The "cortical ribbon sign"

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Abstract

Through a case report of Creutzfeldt-Jakob disease (CJD) featuring the cortical ribbon sign on cranial MRI, this article reviews the pathophysiological mechanism of this specific neuroimaging sign. It proceeds to explore the sign's association with a range of neurological diseases and its significance in diagnosis and differential diagnosis.

Key words

Cortical ribbon sign / Creutzfeldt-Jakob disease / Cytotoxic edema

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Yuanmei PAN, Ying CHEN, Gang WANG. The "cortical ribbon sign"[J]. Journal of Neurology and Neurorehabilitation. 2026, 22(2): 168-172 https://doi.org/10.12022/jnnr.2025-0332

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