颅内静脉窦血栓形成致空蝶鞍：2例报告及文献复习

姚小英; 戴若莲; 管阳太

doi:10.12022/jnnr.2016-0064

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神经病学与神经康复学杂志 ›› 2017, Vol. 13 ›› Issue (1) : 51-57. DOI: 10.12022/jnnr.2016-0064

病例报告

颅内静脉窦血栓形成致空蝶鞍：2例报告及文献复习

姚小英，戴若莲，管阳太

作者信息 +

Empty sella secondary to cerebral venous sinus thrombosis: two case reports and literature review

YAO Xiaoying, DAI Ruolian, GUAN Yangtai

Author information +

文章历史 +

摘要

目的：空蝶鞍是指蛛网膜憩室通过缺损的鞍隔从鞍上池疝入到蝶鞍内。原发性空蝶鞍的形成与垂体病变无关，而与颅内压增高和鞍隔缺损有关。本文旨在探讨临床上慢性颅内高压所致的空蝶鞍形成。方法：报道2例因颅内静脉窦血栓形成引起慢性颅内高压导致空蝶鞍的病例。结果：2例患者均以头痛为主要临床表现，行腰椎穿刺术发现脑脊液压力增高，头颅磁共振静脉造影显示颅内静脉窦血栓形成。在给予抗凝治疗后，2例患者的头痛均有一定程度的好转。其中，1例患者在连续的头颅磁共振成像检查中，发现空蝶鞍程度逐渐加重；另一例患者在随访过程中由无空蝶鞍演变成空蝶鞍。结论：慢性颅内高压可导致空蝶鞍形成，并可引起空蝶鞍程度的加重。

Abstract

Objective: Empty sella has been defined as the herniation of the subarachnoid space into the sella turcica through the defected sellar diaphragm. Primary empty sella (PES) is not related to any known previous diseases of pituitary gland, but is considered to be caused by increased intracranial pressure (ICP), in association with defects of the sellar diaphragm. This case report aims to report the empty sella induced by chronic ICP. Methods: Two cases of empty sella related to chronic intracranial hypertension caused by cerebral venous sinus thrombosis (CVST) were reported. Results: In the present two cases, headache was the main clinical symptom; increased ICP was revealed by lumbar puncture; head magnetic resonance venography (MRV) showed the filling defects of the venous sinuses which implied CVST. The headache in the two cases was relieved gradually after the anticoagulant therapy. The degree of empty sella was aggravated on the head magnetic resonance imaging (MRI) images in one case during follow-up; in another case, the empty sella appeared during follow-up. Conclusion: The empty sella can be caused and aggravated by chronic ICP.

导出引用

姚小英，戴若莲，管阳太. 颅内静脉窦血栓形成致空蝶鞍：2例报告及文献复习[J]. 神经病学与神经康复学杂志. 2017, 13(1): 51-57 https://doi.org/10.12022/jnnr.2016-0064

YAO Xiaoying, DAI Ruolian, GUAN Yangtai. Empty sella secondary to cerebral venous sinus thrombosis: two case reports and literature review[J]. Journal of Neurology and Neurorehabilitation. 2017, 13(1): 51-57 https://doi.org/10.12022/jnnr.2016-0064

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