多系统萎缩（multiple system atrophy，MSA）是一种预后极差的罕见病，目前尚无有效的治疗方法。近年来，非侵入性神经调控技术在神经系统变性疾病中展现出极大的优势。经颅磁刺激（transcranial magnetic stimulation，TMS）作为一种非侵入性神经调控技术，已在多种神经系统疾病的治疗中展现出应用潜力。本文旨在综述TMS治疗MSA的最新研究进展，重点阐述TMS对MSA患者核心运动症状（如帕金森综合征和共济失调）及部分非运动症状的疗效证据，并探讨将TMS广泛应用于MSA临床治疗的可能性。

Multiple system atrophy (MSA) is a rare disease with an extremely poor prognosis, for which no effective treatment currently exists. In recent years, non-invasive neuromodulation techniques have shown significant advantages in the field of neurodegenerative diseases. Transcranial magnetic stimulation (TMS), as a non-invasive neuromodulation technique, has demonstrated potential in the treatment of various neurological disorders. This article aims to review the latest research progress on TMS for MSA, with a particular focus on the evidence of its efficacy against core motor symptoms (such as parkinsonism and ataxia) and some non-motor symptoms in MSA patients. The feasibility of broadly implementing TMS in the clinical management of MSA is also discussed.