肿瘤引发的躯体损害与心理痛苦交互交织，严重影响患者预后。当前，如何在肿瘤临床中构建既符合现代循证要求、又契合本土文化情境的心理干预模式，已成为中西医结合肿瘤学的重要课题。《黄帝内经》言：“形与神俱，而尽终其天年。”深刻揭示了形体与神志的深层统一，这一理念与现代心身医学及脑-体互动机制高度吻合。本文以“形神同治”理念为核心，系统梳理了肿瘤情志失调的中西医病机演变及“五脏藏神”辨证框架，并从整合医学视角出发，探讨了中医临床路径与现代阶梯式分层照护模式的有机接口。通过系统阐释中医心理疗法、五行音乐、针灸及耳穴迷走神经调控等非药物干预手段，结合现代心理治疗技术，本文构建了贯穿肿瘤诊断、治疗、康复及安宁疗护全病程的中西医结合干预策略，旨在为现代心理肿瘤学提供具有本土特色的整合治疗新范式。

The intertwined somatic damage and psychological distress induced by malignant tumors severely compromise patient prognosis. Currently, the construction of psychological intervention models in oncology that both meet modern evidence-based requirements and align with local cultural contexts has become an important endeavor in integrative oncology. The Huangdi Neijing states: "When the body and the spirit are united, they will live to the end of their allotted life span." This passage offers a profound articulation of the fundamental unity between the body and the mind—a conception that resonates closely with modern psychosomatic medicine and the neurobiological mechanisms underlying brain-body interactions. Centering on the concept of "integrated treatment of body and mind," this paper systematically reviews the pathological evolution of cancer-related emotional dysregulation from both Chinese and western medical perspectives, as well as the syndrome differentiation framework of "Five Zang-organs Storing Spirit". Drawing on an integrative medicine outlook, it further explores the organic interface between traditional Chinese medicine clinical pathways and the modern stepped-care model. Through a systematic exposition of non-pharmacological interventions—including Chinese psychological therapies, five-element music therapy, acupuncture, and auricular vagus nerve stimulation—alongside contemporary psychotherapeutic techniques, this paper constructs an integrated Chinese-western intervention strategy spanning the full disease continuum of cancer: from diagnosis and active treatment through rehabilitation and palliative care. The aim is to offer a new integrative therapeutic paradigm with distinctive Chinese characteristics for the advancement of modern psycho-oncology.