肿瘤引发的躯体损害与心理痛苦交互交织，严重影响患者的预后。当前，如何在肿瘤临床中构建既符合现代循证要求、又契合本土文化情境的心理干预模式，已成为中西医结合肿瘤学的重要课题。《黄帝内经》云“形与神俱，而尽终其天年”，深刻揭示了形体与神志的深层统一，这一理念与现代心身医学及脑-体互动机制高度吻合。本文以“形神同治”理念为核心，系统梳理了肿瘤情志失调的中西医病机演变及“五脏藏神”辨证框架，并从整合医学视角出发，探讨了中医临床路径与现代阶梯式分层照护模式的有机接口。本文通过系统阐释中医心理疗法、五行音乐、针灸及耳穴迷走神经调控等非药物干预手段，结合现代心理治疗技术，构建贯穿肿瘤诊断、治疗、康复及安宁疗护全病程的中西医结合干预策略，旨在为现代心理肿瘤学提供具有本土特色的整合治疗新范式。

The intertwined somatic damage and psychological distress induced by malignant tumors severely compromise patient prognosis. Currently, the construction of psychological intervention models in oncology that both meet modern evidence-based requirements and align with local cultural contexts has become an important endeavor in integrative oncology. The traditional Chinese medicine (TCM) theory of “unity of body and mind” (Xing-Shen He Yi) emphasizes the dynamic coupling of the soma and psyche, which highly aligns with modern psychosomatic medicine and the mechanisms of brain-body interaction. From the perspective of integrative medicine, this review systematically delineates the pathogenesis of tumor-related emotional disorders from both TCM and Western medicine, alongside the syndrome differentiation framework of “five Zang-organs storing spirit” (Wu Zang Cang Shen). Furthermore, it explores the organic integration of TCM clinical pathways with modern stepped-care management models. By systematically elucidating non-pharmacological interventions—including TCM psychological therapies, Five-Element music therapy, acupuncture, and auricular vagus neuromodulation—integrated with modern psychotherapeutic techniques, this paper constructs a comprehensive integrative intervention strategy spanning the entire disease trajectory: diagnosis, treatment, rehabilitation, and hospice care. Ultimately, this review aims to provide a novel treatment paradigm with local cultural characteristics for modern psycho-oncology.